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Figure 4 | BMC Systems Biology

Figure 4

From: A module-based analytical strategy to identify novel disease-associated genes shows an inhibitory role for interleukin 7 Receptor in allergic inflammation

Figure 4

Network representation of module formed by genes co-regulated by GATA3 in allergen-challenged CD4+ cells from patients with seasonal allergic rhinitis. The interaction network was generated using Ingenuity pathway analysis. Genes shaded in red were up-regulated whereas green were down-regulated. The color intensity reflects the significance value of the regulation. Solid and dotted lines represent direct and indirect interactions, respectively. Node shapes represent the class of molecule, for example donut shapes represent transcription factors (for detailed information see, http://www.ingenuity.com)

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