Figure 5
From: Dynamic simulations on the mitochondrial fatty acid Beta-oxidation network
Ratios of simulated acyl-CoA concentrations before and after fasting. Ratios of simulated acyl-CoA concentrations before and 30 days after a 20% increase of palmitoyl-CoA (C16). The dynamic change leads to more than two-fold increases of octanoyl-CoA (C8) concentrations for MCAD deficiency (MCADD) and tetradecanoyl-CoA (C14) for LCAD deficiency (LCADD), respectively.