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Figure 4 | BMC Systems Biology

Figure 4

From: Roles of the creatine kinase system and myoglobin in maintaining energetic state in the working heart

Figure 4

Transient changes of myoglobin saturation, phosphate levels, cytoplasmic ATP hydrolysis potential, mitochondrial inner membrane potential, and mitochondrial ATP production rate in the control system. (A.) Myoglobin saturation (SMb). (B.) Cytoplasmic ATP concentration ([ATP]c). (C.) Cytoplasmic creatine phosphate concentration ([CrP]c). (D.) Cytoplasmic inorganic phosphate concentration ([Pi]c). (E.) Cytoplasmic ADP concentration ([ADP]c). (F.) Cytoplasmic ATP hydrolysis potential (-ΔGATPase). (G.) Mitochondrial inner membrane potential (ΔΨ). (H.) Mitochondrial ATP production rate, equal to mitochondrial adenosine nucleotide translocator flux (JANT). All variables are simulated for the time courses of the flow and ATP consumption rate in Figure 3.

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