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Figure 8 | BMC Systems Biology

Figure 8

From: Roles of the creatine kinase system and myoglobin in maintaining energetic state in the working heart

Figure 8

Steady-state average values of ΔG ATPase , [Pi] c , [ADP] c , and [CrP] c plotted against ATP hydrolysis rate ( J ATPase ). Model-predicted average values of -ΔGATPase, normalized [Pi]c, and normalized [ADP]c are plotted over the range of work rate with no clamped concentrations in A-C, with [Pi]c clamped in D-F, and with [ADP]c clamped in G-I. The model predictions are plotted as solid lines and dashed lines for the control and no-CK system, respectively. Model-predicted curves of the control and no-CK system overlap in D-F. The baseline and maximum hydrolysis rates, 0.36 and 1.2 mmol s-1 (liter cell)-1, are indicated by vertical dotted lines.

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