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Table 1 Co-located PPIs in reference and evidence-supported subsets

From: Protein-protein interaction as a predictor of subcellular location

PPI sets

Human

Mouse

Fly

Yeast

 

Total PPI (#)

Co-PPI (#)

Co-PPI (%)

Total PPI (#)

Co-PPI (#)

Co-PPI (%)

Total PPI (#)

Co-PPI (#)

Co-PPI (%)

Total PPI (#)

Co-PPI (#)

Co-PPI (%)

Reference sets

            

Known locations

3298

2115

64%

740

512

69%

540

310

57%

16110

9693

60%

Randomized locations

3298

1045

32%

740

268

36%

540

220

41%

16110

6118

38%

Subsets

            

BPscore

366 (11%)

308

84%

79 (11%)

68

86%

65 (12%)

63

97%

3387 (21%)

3177

94%

DDI

512 (16%)

368

72%

158 (21%)

130

82%

49 (9%)

46

94%

806 (5%)

671

83%

Interologs

134 (4%)

114

85%

73 (10%)

56

77%

22 (4%)

20

91%

256 (2%)

234

91%

DB

581 (18%)

426

73%

105 (14%)

82

78%

264 (49%)

123

47%

9579 (59%)

5943

62%

Method

378 (15%)

280

74%

110 (16%)

75

68%

27 (5%)

24

89%

2879 (20%)

2329

81%

PMID

281 (9%)

213

76%

56 (8%)

46

82%

23 (4%)

21

91%

1706 (11%)

1462

86%

Union of subsets

            

Biological evidence type (BIO)

838 (25%)

642

77%

253 (34%)

207

82%

101 (19%)

94

93%

3825 (24%)

3508

92%

Recorded evidence type (EVI)

793 (23%)

583

74%

216 (30%)

161

75%

295 (54%)

149

51%

9733 (60%)

6087

63%

  1. * The proportion of the reference set covered by total PPIs in each subset is indicated in parentheses.