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Figure 4 | BMC Systems Biology

Figure 4

From: Simple molecular networks that respond optimally to time-periodic stimulation

Figure 4

Response of the IFFL to periodic stimulation in function of σ and τ. Average response <Z > T is plotted in function of σ and τ for an I1FFL motif (Fig 1. (c)) stimulated by a pulsatile signal. Parameters σ and τ are expressed in 1/α units and <Z > T in fraction of κ = β α MathType@MTEF@5@5@+=feaagaart1ev2aaatCvAUfKttLearuWrP9MDH5MBPbIqV92AaeXatLxBI9gBaebbnrfifHhDYfgasaacPC6xNi=xH8viVGI8Gi=hEeeu0xXdbba9frFj0xb9qqpG0dXdb9aspeI8k8fiI+fsY=rqGqVepae9pg0db9vqaiVgFr0xfr=xfr=xc9adbaqaaeGaciGaaiaabeqaaeqabiWaaaGcbaGaeqOUdSMaeyypa0tcfa4aaSaaaeaacqaHYoGyaeaacqaHXoqyaaaaaa@326B@ . Threshold parameter is chosen as θ = 0.8 κ. This surface plot of <Z > T is analytically computed by using eq.(10) given in the Additional File 1.

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