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Figure 5 | BMC Systems Biology

Figure 5

From: Connecting extracellular metabolomic measurements to intracellular flux states in yeast

Figure 5

Clustergram of top reporter metabolites (i.e. in yellow) in ammonium-toxic and potassium-limited conditions. Amino acid perturbation patterns (shown in red) were shown to be consistently scored across conditions, indicating that potassium-limited environments K1 (lowest concentration) and K2 (low concentration) elicited a similar ammonium detoxification response as ammonium-toxic environments N1 (high concentration) and N2 (highest concentration). Metabolites associated with folate metabolism (highlighted in green) are also highly perturbed in ammonium-toxic conditions. Metabolite abbreviations are found in Additional file 1.

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