Effect of variation of the RISC degradation rate (c
) on the repressor R for Model A. Variation of (a) the frequency and (b) the amplitude of oscillation in the Repressor as a function of c4, the RISC degradation rate. Cases 1 and 2 are shown in blue and red respectively. The other parameters, namely the miRNA production rate (c1) and the rate of binding of miRNA to mRNA (c3) are kept fixed at 25 h-1 and 10 h-1 respectively.