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Figure 5 | BMC Systems Biology

Figure 5

From: Genetic and environmental pathways to complex diseases

Figure 5

Pathway Interaction Network. Nodes represent KEGG metabolic and signaling pathways and are connected based on the KEGG database [72]. Node size is reflective of the number of phenotypes associated with the particular pathway based on application of SEPEA (p ≤ 0.003) to gene lists annotated from The Genetic Association Database[1]. Intensity of node color is reflective of the number of environmental factors associated with the particular pathway based on enrichment of gene lists annotated from The Comparative Toxicogenomics Database[15].

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