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Table 1 Global gene expression datasets utilized for validation of metabolic syndrome and neuropsychiatric subnetworks

From: Genetic and environmental pathways to complex diseases

METABOLIC SYNDROME
Condition Species Tissue GEO Acc. Reference
obese/lean Human adipocytes GSE2508 [30]
obese/lean Mouse adipocytes GSE4692 [31]
Familial combined hyperlipedemia Human monocytes GSE11393 [32]
Treatment Species Tissue GEO Acc. Reference
Fenofibrate Rat liver GSE8251 [33]
4-hydroxyphenylretinamide Rat liver GSE3952 [34]
9-cis retinoic acid Rat liver GSE3952 [34]
Targretin Rat liver GSE3952 [34]
Vitamin A deficient diet Rat liver GSE1600 [35]
Omega 3 fatty acids Rat cardiomyocytes GSE4327 [36]
Thiazolidinediones Human 3T3-L1 adipocytes GSE1458 [37]
Atorvastatin Human monocytes GSE11393 [32]
Cyfluthrin Human astrocytes GSE5023 [38]
NEUROPSYCHIATRIC DISORDERS
Condition Species Tissue GEO/EBI Acc. Reference
Bipolar Disorder Human prefrontal cortex GSE12654 [39]
Depression Human prefrontal cortex GSE12654 [39]
Schizophrenia Human prefrontal cortex GSE12654 [39]
Schizophrenia Human frontal cortex E-MEXP-857 [40]
Anxiety Mouse various brain regions GSE3327 [41]
Autism Human lymphoblastoid cell lines GSE7329 [42]
Autism Human whole blood GSE6575 [43]
Treatment Species Tissue GEO Acc. Reference
Chlorpyrifos Human astrocytes GSE5023 [38]
Chlorpyrifos Rat forebrain GSE9751 [44]