Figure 2

T. cruzi core metabolic network model, section. A map illustrating a section of the core metabolic network model of T. cruzi. The model accounts for 144 intracellular and transport reactions, 17 input/output exchange reactions and 1 biomass demand reaction across four compartments: cytosol, mitochondria, glycosome and extracellular space. Reactions colored in green are present in both the full and epimastigote specific reconstructions. Those reactions present only in the full network and not present in the epimastigote (i.e. flux is constrained to zero) are depicted in black. Exchange reactions are shown in red (metabolites allowed to only enter the system), blue (metabolites allowed to only leave the system) and yellow (metabolites allowed to enter and/or leave the system). The map also indicates the lower and upper flux constraints for each reaction shown. For a depiction of the entire model, please see additional file 3: CruziCoreMetabolicNetwork.pdf.