Figure 1
From: Analytical approximations for the amplitude and period of a relaxation oscillator
Schematic oscillator designs. (Left) The repressilator is a delay oscillator here idealized as three symmetric repressive components, P 1 , P 2 , and P 3 , with identical production rates, β , and decay rates, α. (Right) The hysteresis oscillator has interlocked feedback loops involving an activator, A, and a repressor, R, which form a complex, C, with a bimolecular rate constant k. The activator and repressor have baseline production rates β a and β a , with total production rising to β A and β R when the concentration of free activator is high. The activator degrades at rate α A whether free or complexed; the repressor degrades at rate α R but only when free.