Table 1 Comparison of different heuristics.
BowTieBuilder | shortest paths | all shortest paths | all interactions | ||
|---|---|---|---|---|---|
G1-Phase | precision (PPI) | 77% | 77% | 77% | 48% |
recall (PPI) | 77% | 77% | 77% | 77% | |
precision (protein) | 67% | 67% | 67% | 67% | |
recall (protein) | 67% | 67% | 67% | 67% | |
S-Phase | precision (PPI) | 73% | 70% | 59% | 60% |
recall (PPI) | 55% | 60% | 50% | 56% | |
precision (protein) | 86% | 86% | 86% | 86% | |
recall (protein) | 86% | 86% | 86% | 86% | |
MAPK | precision (PPI) | 46% | 46% | 37% | 31% |
recall (PPI) | 37% | 43% | 45% | 41% | |
precision (protein) | 79% | 80% | 69% | 79% | |
recall (protein) | 74% | 78% | 80% | 74% | |
Erb | precision (PPI) | 55% | 40% | 9% | NA |
recall (PPI) | 28% | 25% | 15% | NA | |
precision (protein) | 79% | 72% | 44% | 79% | |
recall (protein) | 56% | 76% | 73% | 56% | |
average | precision (PPI) | 63% | 58% | 46% | 46% |
recall (PPI) | 49% | 51% | 47% | 58% | |
precision (protein) | 78% | 76% | 67% | 78% | |
recall (protein) | 71% | 77% | 77% | 71% |