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Table 2 Statistical evaluation of the significance of the model prediction

From: Reconstruction and logical modeling of glucose repression signaling pathways in Saccharomyces cerevisiae

H0: X/N = 1/3

H1: X/N > 1/3

Δrgt1

Δmig1

Δmig1Δmig2

Δsnf1Δsnf4

Δgrr1

Overall

p -value

6.7 × 10-10

4.8 × 10-5

4.8 × 10-5

1.2 × 10-2

2.1 × 10-1

2.6 × 10-14

  1. P-values for the statistical evaluation of the null hypothesis, H0, tested for whether the observed level of success was due to chance, i.e. that the average proportion of correct predictions (X/N) is 1/3, against the alternative hypothesis that the model yields a higher proportion of true predictions. The test is based on the binomial distribution (cf. Methods)
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BMC Systems Biology

ISSN: 1752-0509

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