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Table 1 Summary of the models generated in this study.

From: Deterministic mathematical models of the cAMP pathway in Saccharomyces cerevisiae

Model name No. of parameters No. of variables Description
PKA Model A 5 9 Deterministic model of the PKA module based on Cazzaniga et al [14]
PKA Model B 5 9 PKA Model A with optimized parameter values
PKA Model C 2 3 Simplified PKA module with mass action kinetics
PKA Model D 2 4 Simplified PKA module with Michaelis-Menten kinetics
Simplified cAMP Model A 16 5 Conceptual model of the entire cAMP pathway
Simplified cAMP Model B 18 6 Simplified Model A modified to include Krh proteins
Complete cAMP Model 27 15 Complete model of the cAMP pathway with estimated parameters