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Table 1 Constants and values used in stochastic simulations

From: Cascading signaling pathways improve the fidelity of a stochastically and deterministically simulated molecular RS latch

Constant Meaning Value Units
k on Association rate 104 M-1s-1
k off Dissociation rate 100 s-1
k cat Catalysis rate 104 s-1
V Volume of reaction space m3
menzyme Mass of enzyme 104 gmol-1
msubstrate Mass of substrate 103 gmol-1
D Diffusion coefficient 10-10 m2s-1
  1. Rate constants were based on kinases and phosphatases from the MAPK pathway, retrieved from the Database of Quantitative Cellular Signalling [33].