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Table 2 List of transcription factors that are known to interact synergistically with SMAD (collected from literature search)

From: An integrative ChIP-chip and gene expression profiling to model SMAD regulatory modules

Cofactors

Target genes

GATA4

IAP, IFABP [74]; INHA [75]

C/EBPβ, E2F4/5, FoxO

p15INK4b [76]; c-MYC, p21Cip1, GADD45A, GADD45B, IER1, CTGF, JAG1, LEMD3, SGK, CDC42EP3, and OVOL1 [77]

STAT3

GFAP; HP[78–80]

LEF/TCF

MYC [81]; Xtwn [52]

TCF/β-catenin, AP1

Gastrin[82, 83]

MYOCD

SM22alpha, Tagln[84]

P53

AFP [85], AFP [56]

SOX9

COL2A1[86]

COUPTF

COL7A1[54].

SP1, SP3

LPL [87]; vimentin [88]

ETS-1

CCN2[89]

NFKappaB and AP1

IL6[90]

HIF1α

VEGF[91]

AP-1

ET1[92]

HNF-4

apolipoprotein C-III[58]

TFE-3

SERPINE1 (PAI-1) [93]

MITF

mmcp-7[94]

OCT-1

GATA2[95, 9]

AP-2

Col7a1[7]

RARγ

human gene promoter construct [59]