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Figure 1 | BMC Systems Biology

Figure 1

From: Exploiting gene deletion fitness effects in yeast to understand the modular architecture of protein complexes under different growth conditions

Figure 1

Comparison of the fitness of yeast strains upon deletion of genes in complexes and other genes. Distributions of strain fitness upon deletion of genes in complexes (red) and genes not part of complexes (blue) in YPD medium. Genes with a fitness of zero are essential. The fitness values of individual genes are partitioned into four categories: 'strong negative effect' (--), 'moderate negative effect' (-), 'weak or no effect' (0) and 'positive effect' (+). Different shades of red illustrate the percentage of genes in complexes (for which we have essentiality data) in the four fitness categories, with deep red corresponding to 100% (1404 genes). Different shades of blue illustrate the percentage of genes not in complexes (for which we have essentiality data) in the four fitness categories, with deep blue corresponding to 100% (3770 genes). Enrichments are given on a log2-scale.

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