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Table 3 Predicted genes for Cluster A and B from the extended gene sets.

From: A dynamic network of transcription in LPS-treated human subjects

Cluster Gene Symbol Gene Name
A CFLAR CASP8 and FADD-like apoptosis regulator
  CXCL1 chemokine (C-X-C motif) ligand 1
  EFNA1 ephrin-A1
  G0S2 G0/G1switch 2
  IL1R1 interleukin 1 receptor, type I
  IL1RN interleukin 1 receptor antagonist
  OLR1 oxidized low density lipoprotein (lectin-like) receptor 1
  PLK3 polo-like kinase 3
  PTX3 pentraxin-related gene, rapidly induced by IL-1 beta
  RUNX1 runt-related transcription factor 1
  TNFAIP6 tumor necrosis factor, alpha-induced protein 6
  TNIP1 TNFAIP3 interacting protein 1
B CASP4 caspase 4, apoptosis-related cysteine peptidase
  CD14 CD14 molecule
  CISH cytokine inducible SH2-containing protein
  GBP1 guanylate binding protein 1, interferon-inducible, 67 kDa
  GBP2 guanylate binding protein 2, interferon-inducible
  GCH1 GTP cyclohydrolase 1
  HSPA1A heat shock 70 kDa protein 1A
  IFI16 interferon, gamma-inducible protein 16
  IFIT3 interferon-induced protein with tetratricopeptide repeats 3
  IFITM1 interferon induced transmembrane protein 1
  IGF1R insulin-like growth factor 1 receptor
  IL10RB interleukin 10 receptor, beta
  IRF2 interferon regulatory factor 2
  ISG15 ISG15 ubiquitin-like modifier
  ISG20 interferon stimulated exonuclease gene 20 kDa
  JAK2 Janus kinase 2
  MX1 myxovirus (influenza virus) resistance 1, interferon-inducible protein p78
  PLSCR1 phospholipid scramblase 1
  RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1
  SOCS1 suppressor of cytokine signaling 1
  STAT2 signal transducer and activator of transcription 2
  TIMP1 TIMP metallopeptidase inhibitor 1
  USP18 ubiquitin specific peptidase 18
  WARS tryptophanyl-tRNA synthetase
  1. Genes that showed high correlation to the average expression profile of a cluster (c > 0.5) were accepted as part of the cluster.