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Table 4 Predicted genes for Cluster A and B form the "no evidence" group

From: A dynamic network of transcription in LPS-treated human subjects

Cluster Category Gene Symbol Gene Name
A Top 10 ETS2 v-ets erythroblastosis virus E26 oncogene homolog 2
   MTF1 metal-regulatory transcription factor 1
   SAMSN1 SAM domain, SH3 domain and nuclear localization signals 1
   IVNS1ABP influenza virus NS1A binding protein
   IFNGR2 interferon gamma receptor 2
   PLAUR plasminogen activator, urokinase receptor
   IL1R2 interleukin 1 receptor, type II
   AZIN1 antizyme inhibitor 1
   EHD1 EH-domain containing 1
   PCNX pecanex homolog
  Related to innate immunity IFNGR2 interferon gamma receptor 2
   IL1R2 interleukin 1 receptor, type II
   MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4
   NCF1 neutrophil cytosolic factor 1
   TXN thioredoxin
   RIPK2 receptor-interacting serine-threonine kinase 2
  Supported by other evidence IFNGR2* interferon gamma receptor 2
   GPR84** G protein-coupled receptor 84
   FCAR** Fc fragment of IgA, receptor for
   GADD45B** growth arrest and DNA-damage-inducible, beta
B Top 10 TRIM5 tripartite motif-containing 5
   GK glycerol kinase
   SP110 SP110 nuclear body protein
   TMEM140 transmembrane protein 140
   CHMP5 chromatin modifying protein 5
   RHBDF2 rhomboid 5 homolog 2
   SAMD9 sterile alpha motif domain containing 9
   DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
   TLE3 transducin-like enhancer of split 3
   TRIM21 tripartite motif-containing 21
  Related to innate immunity CSF2RB colony stimulating factor 2 receptor, beta, low-affinity
   HCK hemopoietic cell kinase
   IL13RA1 interleukin 13 receptor, alpha 1
   TLR1 toll-like receptor 1
   TNFRSF1A tumor necrosis factor receptor superfamily, member 1A
  Supported by other evidence DDX5*** DEAD (Asp-Glu-Ala-Asp) box polypeptide 5
   HERC5*** hect domain and RLD 5
   IFIT2*** interferon-induced protein with tetratricopeptide repeats 2
   OASL*** 2'-5'-oligoadenylate synthetase-like
   SNX10*** sorting nexin 10
   ACSL4*** acyl-CoA synthetase long-chain family member 4
  1. The ten most correlated target genes, as well as genes related to innate immunity (from the fifty most correlated genes) and genes which were supported by other evidence, are shown. *Predicted as a target gene from the motif sequence analysis. **DNA-protein binding detected in LPS stimulation. ***Up-regulated by a mutant of STAT1 which can activate expression in the absence of tyrosine phosphorylation.