Skip to main content

Table 4 Predicted genes for Cluster A and B form the "no evidence" group

From: A dynamic network of transcription in LPS-treated human subjects

Cluster

Category

Gene Symbol

Gene Name

A

Top 10

ETS2

v-ets erythroblastosis virus E26 oncogene homolog 2

  

MTF1

metal-regulatory transcription factor 1

  

SAMSN1

SAM domain, SH3 domain and nuclear localization signals 1

  

IVNS1ABP

influenza virus NS1A binding protein

  

IFNGR2

interferon gamma receptor 2

  

PLAUR

plasminogen activator, urokinase receptor

  

IL1R2

interleukin 1 receptor, type II

  

AZIN1

antizyme inhibitor 1

  

EHD1

EH-domain containing 1

  

PCNX

pecanex homolog

 

Related to innate immunity

IFNGR2

interferon gamma receptor 2

  

IL1R2

interleukin 1 receptor, type II

  

MAP4K4

mitogen-activated protein kinase kinase kinase kinase 4

  

NCF1

neutrophil cytosolic factor 1

  

TXN

thioredoxin

  

RIPK2

receptor-interacting serine-threonine kinase 2

 

Supported by other evidence

IFNGR2*

interferon gamma receptor 2

  

GPR84**

G protein-coupled receptor 84

  

FCAR**

Fc fragment of IgA, receptor for

  

GADD45B**

growth arrest and DNA-damage-inducible, beta

B

Top 10

TRIM5

tripartite motif-containing 5

  

GK

glycerol kinase

  

SP110

SP110 nuclear body protein

  

TMEM140

transmembrane protein 140

  

CHMP5

chromatin modifying protein 5

  

RHBDF2

rhomboid 5 homolog 2

  

SAMD9

sterile alpha motif domain containing 9

  

DDX58

DEAD (Asp-Glu-Ala-Asp) box polypeptide 58

  

TLE3

transducin-like enhancer of split 3

  

TRIM21

tripartite motif-containing 21

 

Related to innate immunity

CSF2RB

colony stimulating factor 2 receptor, beta, low-affinity

  

HCK

hemopoietic cell kinase

  

IL13RA1

interleukin 13 receptor, alpha 1

  

TLR1

toll-like receptor 1

  

TNFRSF1A

tumor necrosis factor receptor superfamily, member 1A

 

Supported by other evidence

DDX5***

DEAD (Asp-Glu-Ala-Asp) box polypeptide 5

  

HERC5***

hect domain and RLD 5

  

IFIT2***

interferon-induced protein with tetratricopeptide repeats 2

  

OASL***

2'-5'-oligoadenylate synthetase-like

  

SNX10***

sorting nexin 10

  

ACSL4***

acyl-CoA synthetase long-chain family member 4

  1. The ten most correlated target genes, as well as genes related to innate immunity (from the fifty most correlated genes) and genes which were supported by other evidence, are shown. *Predicted as a target gene from the motif sequence analysis. **DNA-protein binding detected in LPS stimulation. ***Up-regulated by a mutant of STAT1 which can activate expression in the absence of tyrosine phosphorylation.