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Table 2 Drugs in the minimal hitting sets

From: Optimal drug combinations and minimal hitting sets

NSC Name Mechanism of action
21206 6-aminonicotinamide Antimetabolite
174121 methotrexate derivative Antimetabolite
606698 Rapamycin prodrug mTOR inhibitor
606699 Rapamycin prodrug mTOR inhibitor
147340 Anisomycin hydrochloride NA
646846 bengamide B NA
656238 2-Methyl-4,8-dihydrobenzo [1,2-b:5,4-b']dithiophene-4,8-dione NA
656240 2-Hydroxymethyl-4,8-dihydrobenzo [1,2-b:5,4-b']dithiophene-4,8-dione NA
671526 Toxin.delta.53L NA
674092 Quinoline-4-carboxamide, N, N'-[(1,4-piperazinediyl) bis(3,1-propanediyl)]bis(2-phenyl-, dihydrochloride NA
676495 NA NA
689535 1-methyl-3-(1-pyrazin-2-ylethylideneamino)-1-(2-pyridin-2-ylethyl) thiourea NA
692745 1H-Inden-1-one, 2,3-dihydro-2-[(4-hydroxy-3,5-dimethylphenyl) methylene]-5,6-dimethoxy-, (2E)- NA
623794 1,4-Benzodioxin-2-carboxamide, 6-(4-oxo-4-H-1-benzopyran-2-yl)-N-(3-pyridinylmethyl)- NA
682449 Benzo [1,2-b:4,5-b']dithiophene-4,8-dione, 2-(1-hydroxyethyl)- NA
691039 (7S)-7-hydroxy-1,2,3-trimethoxy-10-methylsulfanyl-6,7-dihydro-5H-benzo [a]heptalen-9-one NA
725983 7-methoxy-5-oxo-8-[3-(9-oxo-9,10-dihydro-4-acridinylcarboxam ido)propoxyl]-(11aS)-1H,2H,3H,5H-bezo [e]pyrrolo [1,2-a][1,4]d iazepine NA
  1. The list of drugs in the minimal hitting sets reported in Table 1. NSC stands for cancer chemotherapy National Service Center number. NA stands for Not Available.