Detailed comparison of TPEs and experimental data. Matches and mismatches between experimental data and TPEs. The matches and mismatches for the different timepoints were combined by assigning +1 to matches,-1 to mismatches and calculating the mean for each perturbation/gene pair. Means close to 1 are green, those close to -1 are colored red. Means close to 0 (equal matches/mismatches) are white. Gray cells indicate perturbation/gene pairs for which no experimental data was available. Expression changes for the perturbed gene were not included in the analysis, because translation was blocked in experiments and transcription was blocked in simulations. For updated experimental data, see .