Territory-specific perturbation effects. Topological perturbation effects of different genes for Alx1-KD, Dri-KD, Ets1-KD, Hnf6-KD and Pmar1-KD at different timepoints and for different embryonic territories (all territories, endoderm, mesoderm, PMC). Rows show the effects of the indicated perturbation on the expression of the respective gene at time points 14, 19, 25, 33, 45 and 66 hpf. For each timepoint, the 4 columns indicate the effects for (from left to right) 1.) the combination of endoderm, mesoderm and PMC, 2.) endoderm alone, 3.) mesoderm alone, 4.) PMC alone. Red indicates a decrease in expression, green an increase in expression, white indicates no effect of the perturbation on the respective gene. Gray fields indicate genes that are not expressed in the given territory.