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Figure 3 | BMC Systems Biology

Figure 3

From: The crosstalk between EGF, IGF, and Insulin cell signaling pathways - computational and experimental analysis

Figure 3

The results of dynamic simulations for the four monitored molecules. Each layer on the graph is a different level of activation of IGF-1R, with top layers corresponding to higher IGF-1R activities. Signal propagation for all edges was set at 0.8, except for the edges IGF-1R-Shc, IR-Shc, IRS-Shc and IGF-1R-β-arrestin whose weights were set as close to zero.

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