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Figure 3 | BMC Systems Biology

Figure 3

From: Hybrid stochastic simplifications for multiscale gene networks

Figure 3

Lambda-phage model, an example of averaged piecewise-deterministic process. a) The cycle to be averaged is in red. Model 1 is the unreduced model, Model 2 is obtained from Model 1 by averaging. The integer labels represent orders of first order rate constants (1 represents the fastest reactions). b) SSA trajectory of the un-averaged model (Model 1). c) PDP trajectory of the averaged PDP (Model 4 which is the first order Kramers-Moyal approximation of Model 2). d) Comparison of estimated steady distribution for trajectories close to the lysogenic attractor (Models 3 and 4 are PDPs, obtained from Models 1 and 2, respectively).

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