Figure 2
From: Metabolism as means for hypoxia adaptation: metabolic profiling and flux balance analysis
Principal component analysis of the metabolic profiles. Average group scores along the first three principal components (PCs). Lines represent shifts from 4-hour hypoxia stimulus. Groups are separated by color according to the code in Figure 1. Figure 2 plots average scores for all 14 groups within the first 3 PC dimensions. The top axes display the average scores along PC 1 and PC 2, and the bottom axes plot PC 1 versus PC 3. Lines are drawn to connect steady state profiles for each group with profiles under acute hypoxia conditions. The direction and magnitude of these lines can be directly mapped to changes in specific metabolites using Figure S1 in the supplementary data.