Figure 3

ATP production in simulations. Simulations of ATP production at a common O₂ uptake rate (4.8 nmol/min/mg protein) for groups starting from their steady state concentrations (20% for naïve controls and 4% for adapted flies). For equivalent oxygen uptake, adapted flies are able to produce more ATP than naïve controls (p < 0.05 for all comparisons of the three groups). The O₂ uptake rate was set near the minimum allowed uptake for all three simulations to produce feasible results. Error bars indicate standard deviation of 100 simulations incorporating the variances of NMR measurements, as detailed in the text. For simplicity, data are shown for males only.