Figure 6From: Metabolism as means for hypoxia adaptation: metabolic profiling and flux balance analysisGene expression differences between adapted and naïve flies. Microarray data mapped to the metabolic reconstruction with a threshold of 10% change in expression. At the pyruvate branchpoint, pyruvate carboxylase is downregulated and pyruvate dehydrogenase upregulated in adapted flies, which matches the regulation of fluxes seen in simulation.Back to article page