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Table 2 Survey of one-component regulatory subnetworks

From: The capacity for multistability in small gene regulatory networks

Subnetwork Dimer formation Monomer binding Dimer binding Multiple equilibria ruled out?
     IG-T IG-K SRG INJ CRNT
ab no no no yes yes yes yes yes
abcd no yes + no no no no no yes
abc no yes - no no no no yes yes
abe yes no no no no yes yes yes
abefg yes no yes + no no no no no
abef yes no yes - no no no yes yes
abcde yes yes + no no no no no yes
abcdefg yes yes + yes + no no no no no
abcdef yes yes + yes - no no no no yes
abce yes yes - no no no no yes yes
abcef yes yes - yes - no no no yes yes
abcefg yes yes - yes + no no no no no
  1. Analysis of twelve gene regulatory subnetworks that consist of one gene and one gene product. The letters that make up the Subnetwork names refer to the constituent reactions listed in Table 1. The entries yes+/- indicate productive/unproductive binding to the gene promoter. The five analytical tools IG-T, IG-K, SRG, INJ, and CRNT are described in the text. In the three cases where multiple equilibria were not ruled out (subnetworks abefg, abcdefg, and abcefg), the CRNT provided example sets of rate constants leading to bistability.