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Table 3 Bootstrap analysis results for two-component regulatory subnetworks

From: The capacity for multistability in small gene regulatory networks

# dimers binding

% of total models

% with multiple equilibria ruled out

0

0.8

26.2 [19.0, 34.4]

1

4.8

19.8 [17.1, 22.9]

2

14.5

12.6 [11.3, 14.1]

3

25.5

8.9 [8.1, 9.9]

4

28.8

4.1 [3.5, 4.7]

5

19.1

1.4 [1.0, 1.9]

6

6.5

0.0

  1. The percentage of two-component subnetworks for which multiple equilibria can be ruled out, based on INJ analysis of ~15,000 randomly selected subnetworks (see text). Results are grouped according to the number of dimer-binding reactions in each subnetwork. Brackets indicate bootstrap 95% confidence intervals calculated by sampling with replacement 10,000 times. Overall, the capacity for multiple equilibria is ruled out by the INJ method for 6.71% [6.31%, 7.11%] of sampled subnetworks.