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Table 3 Steady state analysis for hepatocyte Bid KO Model (Model 5)1

From: Modeling system states in liver cells: Survival, apoptosis and their modifications in response to viral infection

Model A
Steady State A1
Value Model A
Steady State A2
Value Model A
Steady State A3
Value Model A
Steady State A4
Value
Akt* 0,99 Akt* 0 Akt* 0,99 Akt* 0
Akt/PKB 0,79 Akt/PKB 0 Akt/PKB 0,79 Akt/PKB 0
Apaf1 1 Apaf1 0 Apaf1 0 Apaf1 1
Apoptosis 0,98 Apoptosis 0,98 Apoptosis 0 Apoptosis 0,98
Bcl-2/Xl 0 Bcl-2/Xl 1 Bcl-2/Xl 1 Bcl-2/Xl 0
Bcl-2/Xl* 0 Bcl-2/Xl* 1 Bcl-2/Xl* 1 Bcl-2/Xl* 0
Caspase-10 0 Caspase-10 0,85 Caspase-10 0 Caspase-10 0,85
Caspase-3 0,78 Caspase-3 0,95 Caspase-3 0 Caspase-3 0,99
Caspase-6 0,98 Caspase-6 1 Caspase-6 0 Caspase-6 1
Caspase-7 0,93 Caspase-7 0,83 Caspase-7 0 Caspase-7 1
Caspase-8 0 Caspase-8 0,78 Caspase-8 0 Caspase-8 0,78
Caspase-9 1 Caspase-9 0 Caspase-9 0 Caspase-9 1
Cleavage 1 Cleavage 1 Cleavage 0 Cleavage 1
CytC 1 CytC 0 CytC 0 CytC 1
DFF40 1 DFF40 1 DFF40 0 DFF40 1
DFF45 1 DFF45 1 DFF45 0 DFF45 1
Fragmentation 0,85 Fragmentation 0,85 Fragmentation 0 Fragmentation 0,85
Survival Genes 0 Survival Genes 0 Survival Genes 0,99 Survival Genes 0
Degradation 0,93 Degradation 0,93 Degradation 0,9 Degradation 0,93
Caspase 0,01 Caspase 1 Caspase 0,01 Caspase 1
IKK 0,01 IKK 0 IKK 0,93 IKK 0
IkBa 0 IkBa 0 IkBa 0,91 IkBa 0
NFkB 0,01 NFkB 0 NFkB 0,79 NFkB 0
PI3K 0,73 PI3K 0 PI3K 0,73 PI3K 0
Stat3 0 Stat3 0,93 Stat3 0,93 Stat3 0
Survival 0 Survival 0 Survival 0,93 Survival 0
mTor 1 mTor 0 mTor 1 mTor 0
s69 0 s69 0 s69 1 s69 0
tBid 0 tBid 0 tBid 0 tBid 0
  1. 1All interesting nodes of the network are listed together with the activation state for each steady state.