Inferring modules from human protein interactome classes

BMC Systems Biology

Table 3 GO-based annotation results of CFinder and MCODE modules

	module ID	n	n.ex	ex.mean	cor.mean	mf.mean	bp.mean	cc.mean
High	Int-2	5	5	8.33	0.22	0.76	0.7	0.7
	Int-3	5	1	8.54	NA	0.85	0.88	0.84
	Int-4	9	7	9.56	0.43	0.7	0.81	0.92
	Int-7	17	13	8.88	0.17	0.63	0.58	0.66
	Lit-2	5	5	8.33	0.22	0.76	0.7	0.7
	Lit-5	9	9	9.62	0.42	0.59	0.68	0.66
	Lit-9	8	8	9.02	0.62	0.85	0.92	0.82
	Lit-11	10	9	8.17	0.3	0.58	0.74	0.61
	Ortho-8	15	11	8.9	0.15	0.68	0.57	0.67
	Ortho-12	10	9	10.73	0.59	0.83	1	0.98
Medium	Int-18	18	16	9.55	*0.54*	0.45	0.51	0.7
	Ortho-18	17	15	9.65	*0.58*	0.49	0.6	0.72
Low	Int-13	13	11	8.79	0.39	0.45	0.73	0.96
	Lit-4	16	11	7.95	0.24	0.28	0.52	0.58
	Lit-14	11	10	8.79	0.39	0.4	0.72	0.95
	Ortho-7	8	7	9.48	0.41	0.48	0.56	0.61
MCODE	module ID	n	n.ex	ex.mean	cor.mean	mf.mean	bp.mean	cc.mean
High	Int-5	9	7	9.56	0.43	0.7	0.81	0.92
	Lit-4	7	7	8.99	0.13	0.89	0.79	0.71
	Ortho-4	12	9	9.37	0.31	0.51	0.59	0.54
	Ortho-5	9	7	12.92	0.77	0.65	0.78	0.71
Low	Lit-11	9	8	8.34	0.24	0.4	0.59	0.69
	Lit-13	22	20	8.81	0.32	0.33	0.5	0.63
	Ortho-2	6	5	8.08	0.29	0.41	0.78	0.73
	Ortho-10	11	9	8.38	0.38	0.39	0.52	0.67

GO-based annotation results of CFinder andMCODE modules: High (bold font for every GO category), Medium (cor.mean ≧ 0.5), and Low (cor.mean < 0.5) confidence groups.

ISSN: 1752-0509