A quantitative approach to study indirect effects among disease proteins in the human protein interaction network

BMC Systems Biology

Table 2 Strengths of indirect effects between H and O proteins.

The relative strength of two-step-long indirect interactions (A_{H, O}²) mediated by mediators among heart disease and obesity. Column sums would give which H protein is mostly influenced by O proteins (P18825), while row sums would give which O protein is mostly influenced by H proteins (P07550). The largest value (0.123) indicates the strongest indirect effect between the two diseases (corresponding to Q14232, see Table 1).

ISSN: 1752-0509