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Table 2 Strengths of indirect effects between H and O proteins.

From: A quantitative approach to study indirect effects among disease proteins in the human protein interaction network

O\H P08254 P08588 P16671 P17302 P18825 P78504 Q14524 Q9UGJ0 Q9Y4J8
O00253          
O75056    0.0154 0.0155      
P01189          
P07550   0.0867 0.0005 0.0222 0.123     
P13945    0.0013 0.0013      
P25874          
P29120          
P32245          
P37231     0.0071      
P41159         0.0508  
P41968          
P48357          
P52895          
P55851      0.0583     
P55916      0.0583     
P81133          
Q15466          
Q16620   0.0575 0.012       
Q86YN6          
Q9UBU3          
  1. The relative strength of two-step-long indirect interactions (AH, O2) mediated by mediators among heart disease and obesity. Column sums would give which H protein is mostly influenced by O proteins (P18825), while row sums would give which O protein is mostly influenced by H proteins (P07550). The largest value (0.123) indicates the strongest indirect effect between the two diseases (corresponding to Q14232, see Table 1).
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BMC Systems Biology

ISSN: 1752-0509

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