Table 1 One tailed paired Wilcoxon test P-values comparing distribution of local measures of disruption in information flow in metastatic and non-metastatic PIN-mRNA networks across four different breast cancer cohorts.
From: Increased entropy of signal transduction in the cancer metastasis phenotype
Metric | EMC (n= 1903) | Mainz (n= 1900) | Frid (n= 1270) | LoiUnt (n= 1899) |
|---|---|---|---|---|
| 0.001 | 0.01 | 0.54 | 2e-13 |
| 1e-16 | 5e-10 | 1e-12 | 3e-70 |
dS | 2e-16 | 6e-13 | <1e-100 | <1e-100 |
denotes the difference in mean local correlation,
denotes the difference in mean local absolute correlation and dS denotes the differential local entropy. In the case of the non-metastatic networks, values were averaged over 10 distinct bootstraps before computation of the P-values. The number of pairs (nodes) in the test, n, corresponding to the number of nodes in the network with degree ≥ 10 are given.