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Table 2 Practical identifiability analysis for the experimental scheme ES1 with () represents the nominal value for the parameters; δREFis the parameter mean value computed by the Monte-Carlo based approach; δREFis the relative distance between the mean and the nominal computed as , corresponds to the predicted maximum uncertainty of the given parameter and represents the uncertainty with respect to μREFin %.

From: An iterative identification procedure for dynamic modeling of biochemical networks

Parameter θ* μ REF δREF(in %) (in %)
t 1 0.10 1.77 1680 1.79 100.7
t 2 0.10 6.16 6060 3.03 49.1
c 3a 4.00 10-4 4.00 × 10-5 3.09 2.80 × 10-5 6.90
c 4a 0.50 0.50 0.60 0.08 15.9
c 5 3.00 × 10-4 3.07 × 10-4 2.49 1.02 × 10-4 33.1
k 1 2.50 × 10-3 2.45 × 10-3 2.04 5.34 × 10-4 21.7
k 2 0.10 0.13 33.3 0.08 60.2
k 3 1.50 × 10-3 1.18 × 10-3 21.1 8.08 × 10-4 68.3
k prod 2.50 × 10-5 3.25 × 10-5 29.9 3.19 × 10-5 98.3
k deg 1.25 × 10-4 1.63 × 10-4 33.4 1.62 × 10-4 99.9
i 1 2.50 × 10-3 2.40 × 10-3 3.85 6.38 × 10-4 26.5
e 2a 0.01 4.74 × 10-3 374 5.30 × 10-3 110.9
i 1a 1.00 × 10-3 9.74 × 10-4 0.75 2.42 × 10-4 24.3