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Table 3 Practical identifiability analysis for the experimental scheme ES1 with () represents the nominal value for the parameters; μES 1is the parameter mean value computed by the Monte-Carlo based approach; δES 1is the relative distance between the mean and the nominal computed as , corresponds to the predicted maximum uncertainty of the given parameter and represents the uncertainty with respect to μES 1in %.

From: An iterative identification procedure for dynamic modeling of biochemical networks

Parameter

θ*

μ ES 1

δES 1(in%)

(in %)

c 3a

4.00 × 10-4

4.00 × 10-5

0.02

2.20 × 10-5

5.40

c 4a

0.50

0.50

0.66

0.046

9.07

c 5

3.00 × 10-4

3.01 × 10-4

0.26

1.23 × 10-4

40.8

k 1

2.50 × 10-3

2.49 × 10-3

0.46

5.01 × 10-4

20.1

k 2

0.10

0.10

1.97

0.04

44.0

k 3

1.50 × 10-3

1.49 × 10-3

0.95

5.00 × 10-4

33.7

k prod

2.50 × 10-5

2.60 × 10-5

2.90

1.40 × 10-5

53.7

k deg

1.25 × 10-4

1.29 × 10-4

3.41

7.80 × 10-5

60.8

i 1

2.50 × 10-3

2.49 × 10-3

0.26

4.22 × 10-4

16.9

i 1a

1.00 × 10-3

1.00 × 10-3

0.27

1.82 × 10-4

18.1