From: Validation of a constraint-based model of Pichia pastoris metabolism under data scarcity
Ref* | μ | QGlu | QGly | QMet | Qet | OUR | CPR | QP | Yields Exp./Theo. | Consistency** | |||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cmol·kg-1·h-1 | mol·kg-1·h-1 | " | " | " | " | " | mg·g-1·h-1 | Cmol DW/mol | " | ϕ | π | To π = 1 | |
D1 | 3.86 | 0.97 | 0.00 | 0.00 | 0.00 | 2.02 | 2.07 | 0.020 | 3.98 | < 6.62 | 0.03 | 1.00 | 2% |
A1 | 1.88 | 0.00 | 1.09 | 0.00 | 0.00 | 2.16 | 1.56 | 0.000 | 1.73 | < 2.46 | 0.28 | 1.00 | 7% |
A2 | 2.07 | 0.00 | 0.95 | 0.63 | 0.00 | 2.70 | 1.70 | 0.001 | 1.31 | < 2.25 | 1.20 | 0.73 | 12% |
A3 | 1.72 | 0.00 | 0.74 | 1.48 | 0.00 | 3.90 | 2.10 | 0.014 | 0.77 | < 2.25 | 2.81 | 0.25 | 20% |
A4 | 2.02 | 0.00 | 0.57 | 2.33 | 0.00 | 4.85 | 2.21 | 0.024 | 0.70 | < 2.25 | 5.36 | 0.09 | 29% |
B1 | 6.17 | 0.00 | 2.75 | 0.00 | 0.00 | 3.62 | 2.35 | 0.000 | 2.24 | < 2.46 | 0.07 | 1.00 | 4% |
B2 | 6.18 | 0.00 | 2.77 | 1.87 | 0.00 | 7.19 | 4.18 | 0.001 | 1.51 | < 2.25 | 0.88 | 0.82 | 12% |
B3 | 6.24 | 0.00 | 2.23 | 2.73 | 0.00 | 7.20 | 3.60 | 0.012 | 1.26 | < 2.25 | 2.34 | 0.32 | 19% |
C1 | 2.32 | 0.00 | 0.67 | 2.01 | 0.00 | 3.21 | 1.77 | 0.012 | 0.78 | < 2.25 | 0.15 | 1.00 | 5% |
C2 | 2.32 | 0.00 | 0.28 | 3.18 | 0.00 | 3.79 | 2.09 | 0.021 | 0.63 | < 2.25 | 0.74 | 1.00 | 10% |
C3 | 2.32 | 0.00 | 0.00 | 4.02 | 0.00 | 4.22 | 2.33 | 0.022 | 0.52 | < 0.82 | 1.55 > 10 | 0.49 | 15% |
Random | 0-10 | 0-10 | 0-10 | 0-10 | 0-10 | 0-10 | 0-10 | - | 99% > 10 | < 0.1 99% | - | ||
Random | 1.5-6 | 0-2 | 0-2.7 | 0-2.7 | 0-0.1 | 2.1-7.2 | 1.5-4 | - | 86% | < 0.1 95% | - |