Skip to main content

Advertisement

Table 1 Top 50 hub nodes in the InnateDB-curated human innate immunity interactome.

From: Curating the innate immunity interactome

Gene InnateDB ID Ensembl ID Entrez ID Degree BottleNeck
RELA IDBG-57543 ENSG00000173039 5970 104 *
CTNNB1 IDBG-27347 ENSG00000168036 1499 92 *
IRF1 IDBG-42125 ENSG00000125347 3659 92 *
TRAF6 IDBG-40102 ENSG00000175104 7189 90 *
STAT1 IDBG-77617 ENSG00000115415 6772 86 *
AKT1 IDBG-22709 ENSG00000142208 207 81 *
NFKB1 IDBG-31974 ENSG00000109320 4790 75 *
IKBKB IDBG-19987 ENSG00000104365 3551 71 *
EP300 IDBG-8992 ENSG00000100393 2033 70 *
CHUK IDBG-243385 ENSG00000213341 1147 65 *
IRAK1 IDBG-90782 ENSG00000184216 3654 55 *
MAPK1 IDBG-2147 ENSG00000100030 5594 54 *
IRF3 IDBG-63225 ENSG00000126456 3661 51  
MAP3K7 IDBG-94374 ENSG00000135341 6885 50 *
TRAF2 IDBG-92817 ENSG00000127191 7186 49 *
ERBB2IP IDBG-24405 ENSG00000112851 55914 48 *
SNTA1 IDBG-66573 ENSG00000101400 6640 48 *
SQSTM1 IDBG-61811 ENSG00000161011 8878 47 *
STAT3 IDBG-50702 ENSG00000168610 6774 46 *
IKBKG IDBG-91846 ENSG00000073009 8517 45 *
REL IDBG-53133 ENSG00000162924 5966 45  
NFKBIA IDBG-4758 ENSG00000100906 4792 44 *
IRF2 IDBG-46310 ENSG00000168310 3660 42  
CASP3 IDBG-46394 ENSG00000164305 836 41 *
PRKCZ IDBG-86108 ENSG00000067606 5590 41 *
BIRC3 IDBG-69045 ENSG00000023445 330 40 *
IRF4 IDBG-55681 ENSG00000137265 3662 40 *
IRF8 IDBG-45278 ENSG00000140968 3394 40 *
MAPK8 IDBG-73479 ENSG00000107643 5599 40 *
MTOR IDBG-89258 ENSG00000198793 2475 40 *
CASP8 IDBG-78534 ENSG00000064012 841 38 *
IL8 IDBG-23954 ENSG00000169429 3576 38 *
IRF7 IDBG-17225 ENSG00000185507 3665 38  
JUN IDBG-99221 ENSG00000177606 3725 38 *
MAPK14 IDBG-84613 ENSG00000112062 1432 38 *
XIAP IDBG-85142 ENSG00000101966 331 38 *
MAVS IDBG-49080 ENSG00000088888 57506 36 *
IKBKAP IDBG-79889 ENSG00000070061 8518 35 *
TSC1 IDBG-90470 ENSG00000165699 7248 35 *
BIRC2 IDBG-69075 ENSG00000110330 329 34  
RAF1 IDBG-19277 ENSG00000132155 5894 34 *
CUL1 IDBG-46918 ENSG00000055130 8454 33 *
HRAS IDBG-16878 ENSG00000174775 3265 33 *
RIPK1 IDBG-57326 ENSG00000137275 8737 33 *
GZMB IDBG-4054 ENSG00000100453 3002 32 *
NFKB2 IDBG-87893 ENSG00000077150 4791 32  
PIK3R1 IDBG-25037 ENSG00000145675 5295 32 *
MAPK3 IDBG-25745 ENSG00000102882 5595 31  
MYD88 IDBG-25713 ENSG00000172936 4615 31  
PAK1 IDBG-65610 ENSG00000149269 5058 31