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Figure 2 | BMC Systems Biology

Figure 2

From: Systems approach to investigating host-pathogen interactions in infections with the biothreat agent Francisella. Constraints-based model of Francisella tularensis

Figure 2

pH homeostasis predictions by Francisella model i RS605. Robustness diagrams depict the effect of proton flux and ammonium ion flux on growth rates of Francisella as a function of the environment. Left panels show H+ ion effects, while the panels on the right show NH4+ ion effects. Distinct trajectory types are observed in all media. Media used were Chamberlain minimal medium (Chamberlain), Chamberlain medium supplemented with glucose (Chamberlain +glu), and host cell conditions (as described in Additional file 1 [S3]).

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BMC Systems Biology

ISSN: 1752-0509

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