Skip to main content
Figure 7 | BMC Systems Biology

Figure 7

From: Systems approach to investigating host-pathogen interactions in infections with the biothreat agent Francisella. Constraints-based model of Francisella tularensis

Figure 7

Systems Biology approach to novel non intuitive hypothesis generation and testing. Identification of AICAR as a potential master regulator in infection as result of combining multiple diverse data types in the context of a stoichiometric model. FBA can be used on the derived model for Francisella to calculate the functional state and identify AICAR as key node.

Back to article page