Table 1 Cliques of Dtwith corresponding p-values for BCR pathway
From: Gene set analysis exploiting the topology of a pathway
|  | H0: Σ1= Σ2 | H0: μ1= μ2 |
|---|---|---|
Clique | p-value | p-value |
(PLCG2, SYK, BTK, BLNK) | 0.056 | 0.122 |
(PLCG2, SYK, PI3K) | 0.164 | 0.075 |
(PLCG2, CaN) | 0.988 | 0.023 |
(PLCG2, SOS, BLNK) | 0.570 | 0.008 |
(PLCG2, SOS, RaSGRP3) | 0.715 | 0.013 |
(PLCG2, PKCB, BCL10) | 0.942 | 0.002 |
(PLCG2, BCL10, PI3K) | 0.796 | 0.059 |
(CD72, CD22, SHP1) | 0.026 | 0.000 |
(LYN, SYK, BTK, BLNK) | 0.008 | 0.549 |
(LYN, SYK, BTK, SHP1) | 0.000 | 0.475 |
(LYN, CD79) | 0.832 | 0.780 |
(LYN, CD19) | 0.989 | 0.358 |
(LYN, VAV, BLNK) | 0.920 | 0.696 |
(LYN, VAV, RAC) | 0.336 | 0.141 |
(NFAT, CaN) | 0.529 | 0.002 |
(GRB2, BLNK, SOS) | 0.821 | 0.201 |
(Ras, RaSGRP3) | 0.044 | 0.121 |
(Ras, Raf) | 0.243 | 0.182 |
(Raf, MEK1/2) | 0.101 | 0.825 |
(MEK1/2, ERK) | 0.252 | 0.593 |
(ERK, AP1) | 0.028 | 0.026 |
(IKK, BCL10, AKT) | 0.430 | 0.524 |
(IKK, IKB, NFKB) | 0.547 | 0.002 |
(AKT, PI3K, BCL10) | 0.476 | 0.142 |
(AKT, PI3K, SHIP) | 0.558 | 0.215 |
(AKT, GSK3B) | 0.631 | 0.017 |
(CD81, SYK, PI3K) | 0.395 | 0.193 |
(SHIP, FcgRIIB) | 0.980 | 0.443 |
LEU13 | 0.103 | 0.003 |
CD21 | 0.008 | 0.008 |