Table 2 Cliques of Dtwith corresponding p-values for the ERBB pathway
From: Gene set analysis exploiting the topology of a pathway
|  | H0: Σ1= Σ2 | H0: μ1= μ2 |
|---|---|---|
Clique | p-value | p-value |
(EGFR, EGF, TGFA, AR, BTC, EPR) | 0.245 | 0.147 |
(EGFR, PLCG) | 0.233 | 0.006 |
(EGFR, Cbl) | 0.004 | 0.007 |
(EGFR, STAT5) | 0.141 | 0.318 |
(EGFR, Src) | 0.224 | 0.176 |
(EGFR, Crk) | 0.047 | 0.196 |
(EGFR, Nck, Grb2) | 0.018 | 0.104 |
(EGFR, Shc, Grb2) | 0.390 | 0.159 |
(Sos, Grb2, Ras) | 0.031 | 0.145 |
(Ras, MEK, Raf) | 0.022 | 0.030 |
(Ras, MEK, JNKK) | 0.004 | 0.694 |
(Ras, Grb2, JNKK) | 0.048 | 0.757 |
(MEK, JNK, JNKK) | 0.009 | 0.186 |
(MEK, JNK, ERK) | 0.678 | 0.075 |
(ERK, JNK, Elk) | 0.125 | 0.242 |
(ERK, Myc) | 0.515 | 0.101 |
(Src, FAK) | 0.421 | 0.524 |
(Crk, Abl) | 0.000 | 0.135 |
(PAK, Nck, JNKK) | 0.004 | 0.099 |
(JNKK, Nck, Grb2) | 0.011 | 0.190 |
(JNK, Jun) | 0.559 | 0.033 |
(PLCG, CAMK) | 0.930 | 0.012 |
(PLCG, PKC) | 0.127 | 0.048 |