Figure 3
From: A yeast's eye view of mammalian reproduction: cross-species gene co-expression in meiotic prophase
Evaluation of conserved co-expression networks using known meiotic genes in yeast, mice, and humans. Precision is the ratio of known meiotic genes (annotated by the meiosis term GO:0007126) to all metagenes. All metagene pairs in a co-expression network were sorted by P-value significance, and precisions were calculated in 100 pair increments. The random curves were derived from 100 trials of randomly permuting metagene pairs in each network. A. Four networks contain yeast genes. Among the 2,406 yeast genes that belong to metagenes, 72 are known meiotic genes. B. Three networks contain mouse genes. Among the 2,272 mouse genes that belong to metagenes, 19 are known meiotic genes. C. Two networks contain human genes. Among the 2,298 human genes that belong to metagenes, 13 are known meiotic genes.