Skip to main content

Table 1 Positive and negative feedback loops of the three regulators of sporulation*.

From: Prediction of quantitative phenotypes based on genetic networks: a case study in yeast sporulation

Regulator Function Feedback loops
Ime1 P i. Ime1-> Ime1;
   ii. Ime1->Ndt80-> Ime1;
   iii. Ime1->Ime2->Ndt80-> Ime1.
Ime2 P i. Ime2-> Ime2;
   ii. Ime2->Ndt80-> Ime2;
   iii. Ime2--|Sum1--|Ndt80-> Ime2;
   iv. Ime2->Ndt80->Clb1->Cdc28-> Ime2.
Ndt80 P i. Ndt80-> Ndt80;
   ii. Ndt80->Ime2-> Ndt80;
   iii. Ndt80-> Ime2--|Sum1--|Ndt80;
   iv. Ndt80->Ime1-> Ndt80;
   v. Ndt80->Clb1->Cdc28->Ime2-> Ndt80.
Ime1 N i. Ime1-> Ime2/Rim4--|Ime1;
   ii. Ime1->Ndt80->Clb1-> Cln2/Cdc28--|Ime1.
  1. * "-> " means the left node activates the right node and "--|" means the left node represses the right node. "P" and "N" represent that the functions of the feedback loops are positive and negative regulation, respectively.
Back to article page

BMC Systems Biology

ISSN: 1752-0509

Contact us