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Table 1 Pathways significantly over-represented in muscle samples of Weddell seals hybridized on Human U133 expression array.

From: Transformation of metabolism with age and lifestyle in Antarctic seals: a case study of systems biology approach to cross-species microarray experiment

Map Map Folders Cell process p-Value Objects
     present total
Cytoskeleton remodeling Regulatory processes/Cytoskeleton remodeling   1.74E-10 41 83
Cytoskeleton remodeling, TGF, WNT and cytoskeletal remodeling Regulatory processes/Cytoskeleton remodeling   2.60E-07 40 98
Translation, Regulation of translation initiation Regulatory processes/Translation translation 2.89E-07 14 19
* Cytoskeleton remodeling, Role PKA in cytoskeleton reorganisation Protein function/Kinases Regulatory processes/Cytoskeleton remodeling protein kinase cascade 6.50E-07 18 30
* Signal transduction, PKA signaling Protein function/G-proteins/GPCR Protein function/Kinases Protein function/Second messenger second-messenger-mediated signaling, protein kinase cascade, G-protein coupled receptor protein signaling pathway 1.27E-06 15 23
Cell adhesion, Histamine H1 receptor signaling in the interruption of cell barrier integrity Protein function/G-proteins/GPCR Regulatory processes/Cell adhesion G-protein coupled receptor protein signaling pathway, cell adhesion 1.54E-06 20 37
Cytoskeleton remodeling, Regulation of actin cytoskeleton by Rho GTPases Protein function/G-proteins/RAS-group Regulatory processes/Cytoskeleton remodeling small GTPase mediated signal transduction 1.98E-06 14 21
Transcription, Formation of Sin3A and NuRD complexes and their role in transcription regulation Regulatory processes/Transcription transcription 2.81E-06 15 24
Development, Role of HDAC and calcium/calmodulin-dependent kinase (CaMK) in control of skeletal myogenesis Protein function
Second messenger Protein function
Transcription factors Regulatory processes
second-messenger-mediated signaling, transcription, response to extracellular stimulus 4.22E-06 22 45
  1. Only first 10 pathways shown, the complete table is given is Additional File 1. The analysis is performed using GeneGo MetaCore software.