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Table 1 Pathways significantly over-represented in muscle samples of Weddell seals hybridized on Human U133 expression array.

From: Transformation of metabolism with age and lifestyle in Antarctic seals: a case study of systems biology approach to cross-species microarray experiment

Map

Map Folders

Cell process

p-Value

Objects

    

present

total

Cytoskeleton remodeling

Regulatory processes/Cytoskeleton remodeling

 

1.74E-10

41

83

Cytoskeleton remodeling, TGF, WNT and cytoskeletal remodeling

Regulatory processes/Cytoskeleton remodeling

 

2.60E-07

40

98

Translation, Regulation of translation initiation

Regulatory processes/Translation

translation

2.89E-07

14

19

* Cytoskeleton remodeling, Role PKA in cytoskeleton reorganisation

Protein function/Kinases Regulatory processes/Cytoskeleton remodeling

protein kinase cascade

6.50E-07

18

30

* Signal transduction, PKA signaling

Protein function/G-proteins/GPCR Protein function/Kinases Protein function/Second messenger

second-messenger-mediated signaling, protein kinase cascade, G-protein coupled receptor protein signaling pathway

1.27E-06

15

23

Cell adhesion, Histamine H1 receptor signaling in the interruption of cell barrier integrity

Protein function/G-proteins/GPCR Regulatory processes/Cell adhesion

G-protein coupled receptor protein signaling pathway, cell adhesion

1.54E-06

20

37

Cytoskeleton remodeling, Regulation of actin cytoskeleton by Rho GTPases

Protein function/G-proteins/RAS-group Regulatory processes/Cytoskeleton remodeling

small GTPase mediated signal transduction

1.98E-06

14

21

Transcription, Formation of Sin3A and NuRD complexes and their role in transcription regulation

Regulatory processes/Transcription

transcription

2.81E-06

15

24

Development, Role of HDAC and calcium/calmodulin-dependent kinase (CaMK) in control of skeletal myogenesis

Protein function

Second messenger Protein function

Transcription factors Regulatory processes

Development

Myogenesis

second-messenger-mediated signaling, transcription, response to extracellular stimulus

4.22E-06

22

45

  1. Only first 10 pathways shown, the complete table is given is Additional File 1. The analysis is performed using GeneGo MetaCore software.