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Table 4 Simulations of loss of function mutants

From: Single-cell and coupled GRN models of cell patterning in the Arabidopsis thaliana root stem cell niche

Gene

Model A

Model A'

Model B

Model B'

Model A-I

SHR

YES

YES

YES

YES

YES

SCR

YES

YES

YES

YES

YES

MGP

NR

NR

YES

YES

YES

JKD

NR

YES

NR

YES

YES

WOX5

NC

NC

YES

YES

YES

PLT

YES

YES

YES

YES

YES

ARF

YES

YES

YES

YES

YES

Aux/IAA

YES

YES

YES

YES

YES

Auxin

YES

YES

YES

YES

YES

  1. As observed, in most cases simulations recovered the experimentally observed configurations. When we did not recover the expected genetic configurations, we distinguish two situations: not recovered (NR), which indicates that even though experimental data was available it was not recapitulated and not enough data for comparison (NC), which indicates that experimental data was lacking, so in these cases a comparison could not be done. The coupled GRN results are reported in (A-I).