Table 5 Significant biological pathways in the set of differentially expressed genes between regions.
Region comparison (# DE genes) | Pathways | p value (FDR = 0.05) |
|---|---|---|
EC-HIP (1349) | Ossification and bone remodelling | 6.395e-3 |
| Â | Cell cycle G2-M | 8.544e-3 |
| Â | Cardiac development FGF-ErbB signalling | 9.847e-3 |
| Â | Cell cycle-Mitosis | 1.159e-2 |
EC-MTG (567) | Development | 5.836e-5 |
| Â | Transport-RAB3 regulation pathway | 1.695e-4 |
EC-PCC (1685) | Role of 14-3-3 proteins in cell cycle regulation | 1.188e-5 |
| Â | Parkin disorder under Parkinson disease | 1.474e-5 |
| Â | TGF, WNT and cytoskeletal remodelling | 2.738e-5 |
HIP-MTG (403) | Immune response-T cell receptor signalling | 1.947e-6 |
| Â | Immune response-Fc epsilon RI pathway | 3.021e-6 |
| Â | Dopamine D2 receptor transactivation of PDGFR in CNS | 3.335e-6 |
HIP-PCC (259) | Immune response-Function of MEF2 in T lymphocytes | 5.157e-8 |
| Â | Immune response-CCR3 signalling in eosinophils | 1.593e-6 |
| Â | Immune response-Fc epsilon RI pathway | 1.853e-6 |
PCC-MTG (210) | none at FDR = 0.05 | - |