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Table 2 Properties of iMM1415 and comparison with existing models

From: A detailed genome-wide reconstruction of mouse metabolism based on human Recon 1

  iMM1415 Selvarasu et al(2010). Evsikov et al(2009). Quek et al(2008). Sheikh et al(2005).
Dominant reconstruction method Manual Manual Automatic Automatic Manual
Genes 1,415 724 1,060 1,399 473
Reactions 3,724 715 2,018 1,757 0
Compounds 2,774 1,285 1,377 2,104 872
Compartments 8 3 1 3 3
Reactions 3,726 1,494 2,018 2,037 1,220
Demand& Exchange& Biomass reactions 455 0 0 0 0
Cytosol 931 1,085 NA 1,650 618
Mitochondrial 409 161 NA 387 12
Extracellular 473 NA NA NA NA
Golgi 250 NA NA NA NA
Lysosome 194 NA NA NA NA
Ribosome 184 NA NA NA NA
Peroxisome 95 NA NA NA NA
Nucleus 88 NA NA NA NA
Transport 1,101 248 0 64 267
Non-gene associated reactions 1,514 291 0 148 324
Essential genes according to modela 53a 109a NA NA 72
Of which experimental data available 17 20 NA NA NA
% match to experimental data 82% 70% NA NA NA
Produces biomass 1 1 0 1 1
  1. aunder "minimum growth" medium, differences exist in both biomass and minimum growth medium definitions between publications.
  2. NA - not available