Table 2 Properties of iMM1415 and comparison with existing models
From: A detailed genome-wide reconstruction of mouse metabolism based on human Recon 1
| Â | iMM1415 | Selvarasu et al(2010). | Evsikov et al(2009). | Quek et al(2008). | Sheikh et al(2005). |
|---|---|---|---|---|---|
Dominant reconstruction method | Manual | Manual | Automatic | Automatic | Manual |
Genes | 1,415 | 724 | 1,060 | 1,399 | 473 |
Reactions | 3,724 | 715 | 2,018 | 1,757 | 0 |
Compounds | 2,774 | 1,285 | 1,377 | 2,104 | 872 |
Compartments | 8 | 3 | 1 | 3 | 3 |
Reactions | 3,726 | 1,494 | 2,018 | 2,037 | 1,220 |
Demand& Exchange& Biomass reactions | 455 | 0 | 0 | 0 | 0 |
Cytosol | 931 | 1,085 | NA | 1,650 | 618 |
Mitochondrial | 409 | 161 | NA | 387 | 12 |
Extracellular | 473 | NA | NA | NA | NA |
Golgi | 250 | NA | NA | NA | NA |
Lysosome | 194 | NA | NA | NA | NA |
Ribosome | 184 | NA | NA | NA | NA |
Peroxisome | 95 | NA | NA | NA | NA |
Nucleus | 88 | NA | NA | NA | NA |
Transport | 1,101 | 248 | 0 | 64 | 267 |
Non-gene associated reactions | 1,514 | 291 | 0 | 148 | 324 |
Essential genes according to modela | 53a | 109a | NA | NA | 72 |
Of which experimental data available | 17 | 20 | NA | NA | NA |
% match to experimental data | 82% | 70% | NA | NA | NA |
Produces biomass | 1 | 1 | 0 | 1 | 1 |