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Table 1 Overview of the macroscopic growth parameters

From: A multi-level study of recombinant Pichia pastoris in different oxygen conditions

O2

[%]

YDM

[g L-1]

biomass yield

[gYDMgglc-1]

specific Fab conc.

[mgFab3H6gYDM-1]

ethanol

[g L-1]

arabitol

[g L-1]

OUR

[mmol gYDM-1h-1]

CER

[mmol gYDM-1h-1]

21

23.98 ± 1.16

0.47 ± 0.02

0.22 ± 0.01

-

-

2.23 ± 0.03

2.34 ± 0.04

11

22.54 ± 1.83

0.45 ± 0.01

0.38 ± 0.01

0.89 ± 0.16

0.90 ± 0.22

2.26 ± 0.16

2.57 ± 0.16

8

12.58 ± 1.94

0.25 ± 0.01

0.54 ± 0.02

6.85 ± 0.33

2.88 ± 0.31

4.14 ± 0.21

5.62 ± 0.32

  1. Physiological parameters of the 3H6 Fab producing strain grown at normoxic (21%), oxygen-limiting (11%) and hypoxic (8%) conditions in glucose-limited chemostat cultures at D = 0.1 h-1. Values represent the mean ± standard error from three biological replicas. YDM = yeast dry mass; glc = glucose; nd = not detected; OUR = oxygen uptake rate; CER = carbon dioxide evolution rate.