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Table 1 Enriched sets in the list of input genes.

From: Information propagation within the Genetic Network of Saccharomyces cerevisiae

Output Gene

Output Protein Function

Enriched Set

p-value

HAP4

Global regulator of respiratory gene expression

Transcription factor activity

2.723 × 10-7

NRG1

Transcriptional repressor

Ribosome biogenesis

1.230 × 10-6

CDC19

Pyruvate kinase

Regulation of glycolysis

3.732 × 10-5

CDC6

ATP-binding protein required for DNA replication

Ribonuclease MRP activity

6.232 × 10-5

UBC9

SUMO-conjugating enzyme

Post-translational protein modification

1.005 × 10-4

ORC6

Subunit of the origin recognition complex

DNA replication origin binding

3.362 × 10-4

UTP23

Involved in 40 S ribosomal subunit biogenesis

rRNA processing

3.392 × 10-4

SEC61

Forms a channel for SRP-dependent protein transport to/from the ER

Enzyme activator

4.117 × 10-4

YGR067C

Unknown function

ATPase activator activity

6.005 × 10-4

YLR278C

Zinc-cluster protein

Modification with fatty acids

8.531 × 10-4

  1. Enriched sets in the list of input genes for selected output genes in the inferred network. Also listed is the cellular function of the protein encoded by the output gene. P-values are calculated with the hypergeometric test. Enrichment was performed by FunSpec (http://funspec.med.utoronto.ca, as of April 29, 2010).